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Q热并发心内膜炎、肝炎、骨髓损害等已累有报道。1962年在四川发现的慢性Q热病例最初即有“肾炎”的诊断,病程中主要表现为腰骶骨骨髓炎,并先后发生关节炎、心肌炎及心肌梗死等。这些Q热引起的损害可能与免疫复合物有关,但无论在临床或实验上目前尚未见证明Q热感染后形成免疫复合物及其与发病关系的肯定报道。为研究Q热的发病与免疫复合物的关系,本文建立动物实验模型及用胶固素ELISA
Q hot concurrent endocarditis, hepatitis, bone marrow damage have been reported. Chronic Q fever cases found in Sichuan in 1962 were initially diagnosed as “nephritis”. The main manifestations of the disease were lumbosacral osteomyelitis and arthritis, myocarditis and myocardial infarction were successively observed. The damage caused by these Q-heat may be related to the immune complex, but there is no clinical or experimental evidence of the formation of immune complexes after Q-heat infection and its affirmative reports on the pathogenesis. In order to study the relationship between the incidence of Q fever and immune complexes, this paper established animal experimental model and the use of gel-immobilized ELISA