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目的探讨普通型慢性肾小球肾炎的CT灌注成像参数及肾脏损害程度的相关性。方法收集15例普通型慢性肾小球肾炎病例,以肾门平面为靶层面行灌注CT扫描,收集BF、BV、MTT、TTP、PS等参数值,与正常肾脏灌注成像的参数值进行对比性研究。结果本组15例病例中肾皮质区双侧BF、BV明显低于正常值的有9例,1例左侧肾皮质BF、BV高于正常值,9例双侧MTT、TTP高于正常值,10例PS值减低;肾髓质区双侧BF、BV低于正常值有5例,1例BF、BV、MTT、TTP值均增高,10例双侧MTT、TTP高于正常值,PS值减低。结论CT灌注成像参数值可以表达普遍型慢性肾小球肾炎的血流动力学变化,间接反映出肾脏损害程度,是预测疾病转归的方法之一。
Objective To investigate the correlation between CT perfusion imaging parameters and renal damage in common chronic glomerulonephritis. Methods Fifteen cases of common chronic glomerulonephritis were collected. The CT scan was performed on the plane of the kidney as the target layer. The values of BF, BV, MTT, TTP and PS were collected and compared with those of normal renal perfusion imaging the study. Results The BF and BV in bilateral renal cortex in 15 cases were significantly lower than the normal values in 9 cases. The BF and BV of the left renal cortex in one case were higher than the normal values. The bilateral MTT in 9 cases were higher than the normal values , 10 cases of PS value decreased; bilateral medullary area BF, BV lower than normal in 5 cases, 1 case of BF, BV, MTT, TTP values were increased in 10 cases of bilateral MTT, TTP higher than normal, PS Value reduction. Conclusions CT perfusion imaging can express the hemodynamic changes of common chronic glomerulonephritis and indirectly reflect the extent of renal damage, which is one of the methods to predict the outcome of the disease.