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1975年Ludlam等指出,在血栓形成时,由于血小板凝集能够释放出一种特殊的血小板蛋白质即β-凝血球蛋白(β-Thromboglobulin简称β-TG)。测定血浆β-TG可以协助诊断静脉血栓形成,对于监测老年人发生血栓-栓塞症具有决定意义。研究对象和方法本文研究对象是因怀疑静脉血栓形成而入老年病房的患者61例。男性23例,女性38例,年龄65～93岁。全部患者作了详细的心血管系统检查,逐日测定β-TG和用~(125)I-纤维蛋白元作腿部扫描,并测定其半衰期,病故者则行尸检。β-TG是采用快速放射化学免疫法测定。另有年龄
Ludlam et al. (1975) pointed out that during thrombosis, β-thromboglobulin (β-TG), a special platelet protein, can be released due to platelet aggregation. Determination of plasma β-TG can assist in the diagnosis of venous thrombosis, for the monitoring of thrombosis-embolism in the elderly has decisive significance. Subjects and Methods This study was conducted in 61 elderly patients admitted to a ward due to suspected venous thrombosis. 23 males and 38 females, aged 65 to 93 years old. All patients underwent a detailed cardiovascular system examination. Β-TG was measured daily and leg-scanning with ~ (125) I-Fibronectin and its half-life was measured. β-TG is determined by rapid radiochemical immunosorbent assay. Another age