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人流吸宫时强力扩张宫颈可能发生子宫穿孔,远期可能因宫颈损伤在今后妊娠时引起产科并发症,例如宫颈机能不全和早产。吸宫前应用前列腺素可使宫颈易于扩张并降低宫颈损伤的发生率。110例年龄14～35岁妊娠6～12周的初孕妇女参加了本研究,用双盲法随机分成2组,每组55例。对照组应用安慰栓剂(仅含赋形剂),研究组应用16,16-双甲基-反式-Δ~2 PGE_1甲酯阴道栓剂(Cervagem)1mg。二种栓剂均在吸宫前2小时放置。用药前测体温、脉搏、血压,用药后每小
Uterine perforation of the cervix is likely to occur when the abortion of the abortion is aborted, which may cause obstetric complications in future pregnancies due to cervical lesions such as cervical incompetence and premature labor. Prostaglandin before aspiration of the uterus can ease the expansion of the cervix and reduce the incidence of cervical lesions. 110 pregnant women aged 14-35 years old 6-12 weeks of gestation participated in this study. They were randomly divided into two groups (55 in each group) by double-blind method. In the control group, placebo suppository (excipient only) was used. In the study group, 1 mg of 16,16-bis-methyl-trans-Δ-2 PGE1 methyl ester vaginal suppository (Cervagem) was used. Two suppositories were placed in the suction 2 hours ago. Measured before treatment body temperature, pulse, blood pressure, medication after each small