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目的探讨射频消融在扩张型心肌病合并预激综合征中的疗效。方法对6例有显性房室旁道的扩张型心肌病患者在药物治疗的基础上进行射频消融治疗,单纯药物治疗的12例扩张型心肌病作为对照组。术后对患者临床症状的改善进行随访,术前及术后6个月使用二维多普勒彩超测量患者左室舒张末期内径(LVDd)、左室射血分数(LVEF)及测定血浆中B型脑钠肽(BNP)水平。结果全部治疗组病例临床症状均有明显改善,术后LVDd、LVEF、BNP较术前明显改善(P<0.05),与对照组比较差异有统计学意义(P<0.05),无明显并发症。结论射频消融对扩张型心肌病合并预激综合征有较好的疗效,其机制可能与心脏再同步化有关。
Objective To investigate the effect of radiofrequency catheter ablation in dilated cardiomyopathy with Wolff-Parkinson-White syndrome. Methods Six cases of dilated cardiomyopathy with dominant atrioventricular bypass were treated with radiofrequency catheter ablation and 12 cases of dilated cardiomyopathy treated with drug alone were taken as control group. The patients were followed up for improvement of clinical symptoms. Left ventricular end-diastolic diameter (LVDd), left ventricular ejection fraction (LVEF) and plasma B Type brain natriuretic peptide (BNP) levels. Results The clinical symptoms of all treatment groups were significantly improved. The postoperative LVDd, LVEF and BNP were significantly improved compared with those before operation (P <0.05). There was significant difference between the two groups (P <0.05) and no obvious complications. Conclusion Radiofrequency ablation has a good effect on dilated cardiomyopathy with Wolff-Parkinson-White syndrome. The mechanism may be related to cardiac resynchronization.