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目的 探讨采用脱细胞异体真皮基质(ADM)组织补片移植眼表重建术治疗难治性眼表疾病的临床效果.方法 难治性眼表疾病30例(30眼),均伴睑球粘连及假性胬肉,实行ADM移植眼表重建术,术后随访观察6～18个月.结果 30眼睑球粘连及假性胬肉均得到明显改善,角膜新生血管较术前明显减少,角膜透明度改善.24眼恢复正常的眼球运动.结论 ADM治疗难治性眼表疾病操作简单,安全有效.“,”Objective To study the clinical effect of allograft acellular dermal matrix (ADM) transplantation for ocular surface reconstruction in the treatment of refractory ocular surface disorders. Method Thirty cases (30 eyes) of refractory ocular surface disorders combined with symblepharon and pseudopterygium were treated with allograft ADM transplatation for ocular surface reconstruction. Follow-up ranged from 6 to 18 months(average 12.5 months). Results All of 30 eyes with symblepharon and pseudopterygium got obvious relife. The corneal neovascularization of all cases decreased and the transparent degree of cornea improved. All 24 eyes (80%) recovered normal ocular movement. Conclusions Ocular surface reconstruction by ADM transplantation is easy to operate, safe and effective.