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目的探讨培哚普利(雅施达)对Ⅰ～Ⅱ级原发性高血压病的临床疗效。方法选择我院近1年期间门诊的121例原发性高血压病患者,均服用培哚普利(雅施达),4mg/次,1次/晨,共8周。主要观察治疗前和治疗后第8周末的坐位舒张压。结果显示两组的血压在治疗后均有显著的下降(P<0.01),治疗过程中未发现严重不良反应事件。结论培哚普利治疗Ⅰ～Ⅱ级原发性高血压病的疗效较好,且不良反应少,安全性好。
Objective To investigate the clinical efficacy of perindopril in patients with grade Ⅰ ~ Ⅱ essential hypertension. Methods A total of 121 patients with essential hypertension who were treated in our hospital during the recent 1 year were enrolled in perindopril, 4mg / time, once daily for 8 weeks. The main observation before treatment and after treatment at the end of the eighth sitting diastolic pressure. The results showed that both groups had a significant decrease in blood pressure after treatment (P <0.01), and no serious adverse events were observed during the course of treatment. Conclusion The effect of perindopril in treating grade Ⅰ ~ Ⅱ essential hypertension is better, with fewer adverse reactions and better safety.