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本文制备竹节参片并进行生物等效性考察.采用超微粉碎-湿法造粒制备竹节参片;按药典规定进行质量检查;高效液相色谱法测定自制竹节参片和人参皂苷Rg3单剂量灌胃后24小时大鼠的血药浓度,DAS 2.0软件计算分析其药动学参数和相对生物利用度.结果 发现,自制竹节参片质量检查各项符合2015版药典要求,与人参皂苷Rg3相比具有较高的生物利用度.因此可知,本实验竹节参片制各工艺合理、质量可控,口服吸收利用度好,为竹节参片的工业化生产和临床应用提供参考.“,”In the present study,we aimed to prepare Panax japonicus tablets and carry out quality inspection.Panax japonicus tablets were prepared by ultrafine pulverization-wet granulation,and quality inspection was carried out according to Pharmacopoeia regulations.The plasma concentration of animals with self-made Panax japonicus tablets or ginsenoside Rg3 in single-dose intragastric administration was determined by high-performance liquid chromatography (HPLC).The pharmacokinetic parameters and relative bioavailability were calculated by DAS 2.0 software.The quality inspection of self-made Panax japonicus tablets met the requirements of Chinese Pharmacopoeia (2015 edition),and this preparation had high bioequivalence of ginsenoside Rg3.The preparation of Panax japonicus tablets was reasonable and highly qualified.Moreover,this new Panax japonicus preparation showed better profiles in oral absorption and utilization.This study provided evidence for the industrial production and clinical application of Panax japonicus tablets.