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目的 比较羟考酮注射液与芬太尼注射液在腹腔镜下子宫肌瘤剔除术后的镇痛效果与安全性.方法 60例行腹腔镜下子宫肌瘤剔除术患者,ASA Ⅰ～Ⅱ级,年龄25岁～42岁,BMI≤35 kg/m2.依数字表法均分为两组,手术结束前15 min,O组静脉给予羟考酮注射液0.15 mg/kg,F组予芬太尼注射液0.00015 mg/kg,观察两组患者术后拔管时间、纪录术后T1、T2、T3、T4、T5、T6和T7VAS疼痛评分及术后24 h内恶心、呕吐、皮肤瘙痒、呼吸抑制等不良反应发生情况.结果 两组患者拔管时间比较无统计学差异;O组患者VAS评分在T4、T5时点降低,O组患者术后恶心、呕吐发生例数明显减少.结论 盐酸羟考酮注射液用于腹腔镜下子宫肌瘤剔除术后镇痛疗效确切,起效快,镇痛持续时间长,不良反应较少.“,”Objective To compare the effect and safety of oxycodone injection and fentanyl injection for postoperative analgesia in patients undergoing laparoscopic myomectomy.Methods Sisty ASA Ⅰ ～ Ⅱ patients,aged 25 to 42 years old,BMI≤35 kg/m2,scheduled for laparoscopic myomectomy.All patients were divided into two groups,oxycodone 0.15 mg/kg for group O and fentany 0.00015 mg/kg for group F were injected intravenously 15 min before the end of surgery.The postoperative extubation time,the VAS of T1,T2,T3,T4,T5,T6,and T7 and the adverse reactions of nausea,vomiting,itchy skin,respiratory depression should be observed and recorded.Results There was no significant different in extubation time;The VAS score of group O reduced in T4 and T5 point,patients with postoperative nausea and vomiting of group O reduced significantly.Conclusion Postoperative analgesia with oxycodone for laparoscopic myomectomy is efficacy,working fast,duration long and with less adverse reaction.