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目的探讨青岛市肺癌发生的主要相关因素,为制定肺癌的防治措施提供依据。方法对青岛市106例原发性肺癌进行1:1配对病例对照研究,通过条件Logistic回归单因素分析和多因素分析筛选主要相关因素。结果单因素分析结果显示,肺结核、生活压力、烟熏食品、煎炸食品、厨房油烟以及吸烟史为肺癌的危险因素(P<0.10),保护性因素有常吃蔬菜、心情愉快及喜欢热闹(P<0.10)。多因素分析结果表明,厨房油烟、烟熏食品、生活压力和吸烟史可能是肺癌的主要危险因素,OR(95%CI)分别为3.595(2.231～5.793),2.012(0.887～4.567),2.398(1.470～3.913)和2.677(1.039～6.902);喜欢热闹(OR=0.292,95%CI:0.174～0.490)可能是保护性因素。结论厨房油烟、烟熏食品、生活压力和吸烟史可能是青岛市居民肺癌发生的主要危险因素。
Objective To investigate the main related factors of lung cancer in Qingdao and provide evidence for the prevention and treatment of lung cancer. Methods 106 patients with primary lung cancer in Qingdao 1: 1 matching case-control study, by conditional Logistic regression analysis of single-factor and multivariate analysis of key factors. Results The results of univariate analysis showed that tuberculosis, life stress, smoked foods, fried foods, kitchen fumes and smoking history were the risk factors of lung cancer (P <0.10). The protective factors were eating vegetables, being in a good mood and enjoying lively P <0.10). Multivariate analysis showed that smoke fumes, smoked foods, life stress and smoking history were the major risk factors for lung cancer. OR (95% CI) were 3.595 (2.231-5.703), 2.012 (0.887-4.567), 2.398 1.470 ~ 3.913) and 2.677 (1.039 ~ 6.902); like lively (OR = 0.292,95% CI: 0.174 ~ 0.490) may be protective factors. Conclusion Kitchen fume, smoked food, life stress and smoking history may be the main risk factors of lung cancer in Qingdao residents.