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目的了解某市无偿献血人群HIV的感染情况。方法采用2种不同厂家的ELISA试剂,对825 351名献血者的标本进行抗-HIV、抗-HCV及HBsAg筛查,并将抗-HIV筛查阳性的标本采用免疫印迹法确认。结果 2003-2010年抗-HIV确认阳性94例,阳性率依次为12.02/10万、11.21/10万、16.52/10万、14.51/10万、12.39/10万、10.14/10万、7.63/10万、11.03/10万,平均感染率为12.03/10万,其中男性高于女性,各年龄组间差异有统计学意义(P<0.05)。HIV与HCV、HBV存在合并感染,以与HCV合并感染率最高,占54.3%。结论在无偿献血招募、体检过程中加强排查,适时调整检测方法,进一步保障血液的安全。
Objective To understand the HIV status of unpaid blood donors in a certain city. Methods Totally 825 351 blood donors were screened by anti-HIV, anti-HCV and HBsAg using two kinds of ELISA reagents from different manufacturers, and the anti-HIV screening positive samples were confirmed by immunoblotting. Results The positive rates of anti-HIV in 2003-2010 were 94 cases, the positive rates were 12.02 / 100000, 11.21 / 100000, 16.52 / 100000, 14.51 / 100000, 12.39 / 100000, 10.14 / 100000, 7.63 / 10 The average infection rate was 12.03 / 100000, of which males were higher than females, with a significant difference among all age groups (P <0.05). HIV and HCV, HBV co-infection, in order to merge with HCV highest prevalence, accounting for 54.3%. Conclusion In voluntary blood donation and medical examination, we stepped up the investigation and adjusted the testing methods in time to further ensure the safety of blood.