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目的对比不同入路手术治疗大肝癌的临床疗效。方法将2012年9月—2014年3月漯河市第二人民医院收治的行手术治疗的大肝癌患者,筛选前入路肝切除术患者33例(观察组)和传统入路肝切除术35例(对照组),比较不同入路治疗大肝癌的疗效。结果两组患者手术时间、转ICU例数、术后并发症发生率、术后6个月肿瘤复发率及患者生存率对比无统计学意义(P>0.05),观察组术中出血量、大出血例数、输血量、住院时间均少于对照组(P<0.05),切除的肿瘤组织直径大于对照组,术后1、3年生存率高于对照组,对比差异有统计学意义(P<0.05)。结论前入路肝切除术能降低术中输血风险,减少出血量,并在一定程度内改善患者生存率。
Objective To compare the clinical effects of different approaches for the treatment of large hepatocellular carcinoma. Methods From September 2012 to March 2014, Luohe Second People’s Hospital underwent surgical resection in patients with large hepatocellular carcinoma. Thirty-three patients (observation group) and 35 patients underwent hepatectomy (Control group) to compare the efficacy of different approaches to treat large hepatocellular carcinoma. Results There were no significant differences in the operation time, the number of ICU transfusions, the incidence of postoperative complications, the recurrence rate at 6 months and the survival rate of patients in both groups (P> 0.05). The intraoperative blood loss, hemorrhage (P <0.05). The diameter of resected tumor tissue was larger than that of the control group. The postoperative 1 and 3 year survival rates were higher than those of the control group (P <0.05), and the difference was statistically significant (P < 0.05). Conclusion Anterior approach hepatectomy can reduce the risk of intraoperative blood transfusion, reduce the amount of bleeding, and to a certain extent, improve the survival rate of patients.