论文部分内容阅读
目的 :从病理角度探索非小细胞肺癌纵隔淋巴结 (N2 )转移的特点。方法 :为 10 0 3例非小细胞肺癌患者行肺切除及淋巴结清除术 ,对 334例 N2 淋巴结转移进行临床病理分析。结果 :病理类型与 N2 转移关系密切 ,鳞癌 N2 转移率显著低于腺癌、腺鳞癌 ;N2 转移率随肿瘤长径增加而增加 ;N2 转移淋巴结的分布范围较为广泛 ,最密集的部位是第 3、7、5组淋巴结 ;中心型肺癌 N2 转移率明显高于周围型肺癌。结论 :为获得根除性切除 ,广泛、彻底清除同侧肺门、支气管和纵隔淋巴结是十分必要的。
Objective: To explore the characteristics of mediastinal lymph node (N2) metastasis in non-small cell lung cancer from the pathological point of view. Methods: One hundred and thirty-three non-small cell lung cancer patients underwent lung resection and lymph node dissection, and 334 cases of N2 lymph node metastasis were analyzed clinically and pathologically. Results: The pathological types were closely related to the metastasis of N2. The metastasis rate of N2 in squamous cell carcinoma was significantly lower than that in adenocarcinoma and adenosquamous carcinoma. The metastatic rate of N2 increased with the increase of tumor diameter. The distribution of N2 metastatic lymph nodes was extensive and the most dense part was Group 3, 7, 5 lymph nodes; central lung N2 metastasis was significantly higher than peripheral lung cancer. Conclusion: To obtain radical resection, it is necessary to extensively and thoroughly remove ipsilateral hilar, bronchus and mediastinal lymph nodes.