Empathy for Distress in Humans and Rodents

来源 :神经科学通报(英文版) | 被引量 : 0次 | 上传用户:gf_lucky
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Empathy is traditionally thought to be a unique ability of humans to feel,understand,and share the emotional state of others.However,the notion has been greatly challenged by the emerging discoveries of empathy for pain or distress in rodents.Because empathy is believed to be fundamental to the formation of prosocial,altruistic,and even moral behaviors in social animals and humans,studies associated with decoding the neural circuits and unraveling the underlying molecular and neural mechanisms of empathy for pain or distress in rodents would be very important and encouraging.In this review,the author set out to outline and update the concept of empathy from the evolutionary point of view,and introduce up-to-date advances in the study of empathy and its neural correlates in both humans and rodents.Finally,the author highlights the perspectives and challenges for the further use of rodent models in the study of empathy for pain or distress.
其他文献
Transgenic mice carrying mutations that cause Autism Spectrum Disorders (ASDs) continue to be valuable for determining the molecular underpinnings of the disorders.Recently,researchers have taken advantage of such models combined with Cre-loxP and similar
A number of studies have indicated that disorders of consciousness result from multifocal injuries as well as from the impaired functional and anatomical connectivity between various anterior forebrain regions.However,the specific causal mechanism linking
Parkinson\'s disease (PD) is the second most common neurodegenerative disease and is typically associated with progressive motor and non-motor dysfunctions.Currently,dopamine replacement therapy is mainly used to relieve the motor symptoms,while its lon
Facial and vocal expressions are essential modalities mediating the perception of emotion and social communication.Nonetheless,currently little is known about how emotion perception and its neural substrates differ across facial expression and vocal proso
Modeling brain disorders has always been one of the key tasks in neurobiological studies.A wide range of organisms including worms,fruit flies,zebrafish,and rodents have been used for modeling brain disorders.However,whether complicated neurological and p
Spinal cord stimulation (SCS) is a promising technique for treating disorders of consciousness (DOCs).However,differences in the spatio-temporal responsiveness of the brain under varied SCS parameters remain unclear.In this pilot study,functional near-inf
Alzheimer\'s disease (AD) is characterized by decreased neuronal activity and atrophy,while hyperactivity of neurons seems to make them resistant to aging and neurodegeneration,a phenomenon which we have paraphrased as\'use it or lose it\'.Our hypot
Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorders characterized by impaired social interactions,communication deficits,and repetitive behavior.Although the mechanisms underlying its etiology and manifestations are poorly un
In the present study we explored the different patterns of volumetric atrophy in hippocampal subregions of patients with left and right mesial temporal lobe epilepsy with hippocampal sclerosis (TLE-HS).Meanwhile,the memory impairment patterns in Chinese-s
期刊
Pain is a subjective and complex phenomenon.Its complexity is related to its heterogeneity:multiple component processes,including sensation,affect,and cognition,contribute to pain experience and reporting.These components are likely to be encoded in distr