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目的建立诊断轻微肝性脑病(MHE)的有效数字连接试验(NCT)-A、数码符号试验(DST)等简易智能测试的正常范围。方法选择至少接受9年以上教育的健康志愿者160名,按年龄分为＜35岁组、35～44岁组、45～54岁组和55～64岁组,全部接受NCT-A、DST等简易智能测试,建立与年龄相关的正常人群均值及标准差,以均数±2标准差作为MHE的诊断标准,用于检测106例肝硬化患者。结果160名健康志愿者的NCT-A在＜35岁组、35～44岁组、45～54岁组和55～64岁组分别为(25．1±4．6)s、(32．1±6．8)s、(38．6±7．1)s和(49．3±6．3)s,DST分数分别为49．9±4．7、44．6±4．8、38．5±5．0和35．4±4．7。106例肝硬化患者以此为标准,诊断出MHE患者31例(29．2%)。结论NCT-A、DST等简易智能测试可用于MHE的诊断,并应建立与年龄相关的正常范围。
Objective To establish a normal range of simple intelligence tests such as Effective Digital Connectivity Test (NCT) -A and Digital Signage Test (DST) for the diagnosis of mild hepatic encephalopathy (MHE). Methods A total of 160 healthy volunteers with at least 9 years of education were enrolled in this study. They were divided into three groups according to their age: 35 years old, 35 to 44 years old, 45 to 54 years old and 55 to 64 years old. All received NCT-A, DST, etc. Simple and intelligent test to establish the age-related normal population mean and standard deviation, mean ± 2 standard deviation as the diagnostic criteria of MHE, for the detection of 106 patients with liver cirrhosis. Results The NCT-A of 160 healthy volunteers were (25.1 ± 4.6) s, (32.1 ± 4.6) s, 35-44 years old, 45-54 years old and 55-64 years old respectively ± 6.8) s, (38.6 ± 7.1) s and (49.3 ± 6.3) s respectively. The DST scores were 49.9 ± 4.7,44.6 ± 4.8,38 .5 ± 5.0 and 35.4 ± 4.7.106 patients with cirrhosis as the standard, 31 patients (29.2%) were diagnosed as having MHE. Conclusions Simple intelligent tests such as NCT-A and DST can be used for the diagnosis of MHE, and the age-related normal range should be established.