论文部分内容阅读
目的针对A型肉毒毒素治疗老年人原发性难治性三叉神经痛的效果进行分析研究。方法 80例老年原发性难治性三叉神经痛患者随机分为对照组和研究组,每组40例。对照组患者采用卡马西平治疗,研究组患者采用A型肉毒毒素治疗,对两组患者的临床治疗效果、不良反应进行比较分析。结果本次研究中,研究组患者的临床治疗总有效率为95.00%,对照组为77.50%,两组总有效率比较差异具有统计学意义(P<0.05)。研究组患者的不良反应发生率为2.50%,对照组为15.00%,两组不良反应发生率比较差异具有统计学意义(P<0.05)。结论在原发性难治性三叉神经痛患者的治疗中,A型肉毒毒素的应用可以明显的改善患者的临床症状,缓解患者的疼痛,同时降低不良反应的发生,有良好的临床治疗效果,可以将其广泛的应用。
Objective To analyze the effect of botulinum neurotoxin A in the treatment of primary refractory trigeminal neuralgia in the elderly. Methods Eighty elderly patients with primary refractory trigeminal neuralgia were randomly divided into control group and study group, 40 cases in each group. Patients in the control group were treated with carbamazepine. Patients in the study group were treated with botulinum toxin type A, and the clinical effects and adverse reactions in the two groups were compared. Results In this study, the total effective rate of clinical treatment was 95.00% in the study group and 77.50% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). The incidence of adverse reactions was 2.50% in the study group and 15.00% in the control group. There was significant difference in the incidence of adverse reactions between the two groups (P <0.05). Conclusions In the treatment of patients with primary refractory trigeminal neuralgia, the application of botulinum toxin type A can significantly improve the clinical symptoms, relieve the patient’s pain, reduce the incidence of adverse reactions, and have a good clinical therapeutic effect , Can be its wide range of applications.