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中药川芎具有行气活血、祛风止痛、温通血脉之功效。川芎嗪为川芎的主要成分,是一种吡嗪类生物碱。现代医学表明川芎嗪(TMP)具有解痉、降低血管阻力、保护血管内皮细胞、抗血小板凝集、Ca~(2+)拮抗、抗纤维化等作用。边晓丽等通过实验发现TMP及其代谢产物均具有很强的羟自由基清除作用。临床广泛用于充血性心力衰竭、器官组织纤维
Traditional Chinese medicine Chuanxiong has the effect of activating qi and activating blood circulation, removing wind-chilling pain and warm blood circulation. Ligustrazine is a main component of Chuanxiong and is a pyrazine alkaloid. Modern medicine shows that Ligustrazine (TMP) has the effects of spasmolysis, reduction of vascular resistance, protection of vascular endothelial cells, anti-platelet aggregation, Ca 2+ antagonism and anti-fibrosis. Xiaoli Xiao et al found through experiments that TMP and its metabolites all have strong hydroxyl radical scavenging effects. Widely used in clinical congestive heart failure, organ tissue fibers