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目的:分析两种标准空腹血糖受损人群葡萄糖负荷后血糖代谢特点。方法:对3828名40岁以上居民进行流行病学调查,对空腹血糖≥5.6mmol/L者行75g葡萄糖负荷试验,据不同空腹血糖受损诊断标准分析负荷后2h血糖代谢情况。结果:在以空腹血糖为6.1mmol/L为切点诊断的245例空腹血糖受损(IFG)人群中,糖耐量减低(IGT)的患病率为41.22%,女性(25.71%)高于男性(15.51%);2型糖尿病(T2DM)患病率为20.82%,女性(11.84%)高于男性(8.98%)。在以空腹血糖为5.6mmol/L为切点诊断的627例空腹血糖受损人群中,糖耐量减低的患病率为37.00%,女性(23.76%)高于男性(13.23%);2型糖尿病患病率为13.88%,女性(9.52%)高于男性(4.63%)。结论:以空腹血糖为5.6mmol/L和6.1mmol/L为切点诊断的空腹血糖受损人群葡萄糖负荷后2h血糖代谢异常率分别为50.88%和62.04%,患病率女性均高于男性。
OBJECTIVE: To analyze the characteristics of blood glucose metabolism after glucose load in two standard impaired fasting glucose patients. Methods: 3828 residents over the age of 40 were investigated by epidemiology. The fasting glucose≥5.6mmol / L was given 75g glucose load test, and the blood glucose metabolism was analyzed 2h after loading according to the diagnostic criteria of impaired fasting glucose. Results: The prevalence of impaired glucose tolerance (IGT) was 41.22% in 245 fasting plasma glucose (IFG) patients diagnosed at a cut-off point of 6.1 mmol / L, and was higher in women (25.71%) than in men (15.51%). The prevalence of type 2 diabetes mellitus (T2DM) was 20.82% and that of women (11.84%) was higher than that of men (8.98%). The prevalence of impaired glucose tolerance was 37.00% in 627 impaired fasting plasma glucose patients diagnosed at a fasting glucose of 5.6 mmol / L, and higher in women (23.76%) than in men (13.23%). Type 2 diabetes The prevalence rate was 13.88%, women (9.52%) than men (4.63%). CONCLUSION: The abnormal glucose metabolism rates at 2h after glucose load in fasting glucose-impaired subjects diagnosed by fasting blood glucose of 5.6mmol / L and 6.1mmol / L are 50.88% and 62.04%, respectively. The prevalence rate of female patients is higher than that of men.