C蛋白系由肝脏合成的一种维生素K依存性血浆糖蛋白,本身属酶原,在血管内皮细胞辅助因子参与下经微量α—凝血酶激活,提高效价2万倍。活化型C蛋白为一种抗凝血酶,它通过限位蛋白水解作用,选择性地使活化型凝血因子Ⅴ和Ⅷ失活发挥抗凝作用。此外C蛋白还有抑制凝血酶原形成和阻止血浆纤维蛋白形成作用。 Protein C, a vitamin K-dependent plasma glycoprotein synthesized by the liver, is an enzyme that itself is activated by microalbumin-thrombin with the involvement of vascular endothelial cofactors, raising potency 20,000 times. Activated protein C is an antithrombin that selectively anticoagulants by inactivating activated coagulation factors Ⅴ and Ⅷ by proteolytic cleavage. In addition protein C also inhibit the formation of prothrombin and prevent the formation of plasma fibrin.