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目的探讨维生素K1联合孟鲁司特钠治疗毛细支气管炎的效果及对症状消失时间的影响。方法选择2012年3月—2014年4月于上栗县人民医院接受治疗的112例毛细支气管炎患儿,根据治疗方案不同分为研究组和对照组,每组56例。对照组患儿给予常规治疗,研究组患儿在对照组基础上给予维生素K1联合孟鲁司特钠治疗。比较两组患儿临床症状消失时间、临床效果。结果研究组患儿肺部啰音消失时间、咳嗽消失时间及喘憋消失时间均短于对照组,总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后两组患儿均未发生严重的不良反应。结论维生素K1联合孟鲁司特钠治疗毛细支气管炎的效果显著,症状消失时间短。
Objective To investigate the effect of vitamin K1 combined with montelukast sodium on bronchiolitis and its effect on the disappearance of symptoms. Methods From March 2012 to April 2014, 112 children with bronchiolitis who were treated in Shangli County People’s Hospital were divided into study group and control group according to different treatment plans, with 56 cases in each group. Children in the control group were given routine treatment. The children in the study group were given vitamin K1 and montelukast sodium on the basis of the control group. Comparison of two groups of children clinical symptoms disappear time, clinical effect. Results The pulmonary rales disappeared, cough disappeared and wheezing disappeared in the study group were shorter than the control group, the total effective rate was higher than the control group, the difference was statistically significant (P <0.05). After treatment, no serious adverse reactions occurred in both groups. Conclusion Vitamin K1 combined with montelukast sodium treatment of bronchiolitis significant effect, symptoms disappear time is short.