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作者评价了编码流感病毒TyIr83和HK97株血凝素(HA)的DNA疫苗在小鼠中的同源和异源保护作用。用巨细胞病毒立即早期启动子和鸡β肌动蛋白启动子将HA基因的全长CDNA拷贝分别克隆到表达载体pJW4303和pCAGGS/MCS获得pTyIrHA和PH?
The authors evaluated the homologous and heterologous protection of DNA vaccines encoding hemagglutinin (HA) of influenza viruses TyIr83 and HK97 in mice. The full-length CDNA copies of the HA gene were cloned into the expression vectors pJW4303 and pCAGGS / MCS, respectively, using the cytomegalovirus immediate early promoter and chicken β-actin promoter to obtain pTyIrHA and PH?