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目的:对《化妆品安全技术规范》2015年版和中国药典2015年版中残留溶剂检测方法的异同进行了归纳与总结,为《化妆品安全技术规范》中残留溶剂检测方法的提高完善提供参考。方法:分别比较分析了《化妆品安全技术规范》2015年版和中国药典2015年版中检测残留溶剂的种类和限度、残留溶剂检测方法的特点。结果:中国药典残留溶剂的测定方法更为详细具体,《化妆品安全技术规范》残留溶剂的测定方法是一种通用的检测方法,所使用的方式方法及流程可扩展至更多溶剂的测定,部分有检测方法的溶剂缺乏限度。结论:建议《化妆品安全技术规范》增加通用方法能检测的残留溶剂的种类,参照中国药典对化妆品中限用的残留溶剂制定类似药典的限度表,对化妆品残留溶剂的控制将更加完善,确保产品的质量安全。
OBJECTIVE: To summarize the similarities and differences of the residual solvent detection methods in the 2015 edition of “Cosmetic safety specification” and the Chinese Pharmacopoeia 2015 edition, and provide references for improving and perfecting the residual solvent detection method in the “Technical Code of Cosmetics Safety”. Methods: The types and limits of residual solvents and residual solvent detection methods in the 2015 edition of “Technical Code of Cosmetics Safety” and the Chinese Pharmacopoeia 2015 were compared and analyzed respectively. Results: The method for determination of residual solvents in Chinese Pharmacopoeia was more detailed and specific. The method for determination of residual solvents in “Technical Code of Cosmetics Safety” is a general detection method. The methods and procedures used can be extended to the determination of more solvents. Part There is a limit of solvent shortage for the test method. Conclusions: It is suggested that the “Cosmetic safety specification” increase the types of residual solvents that can be detected by the general method. With reference to the Chinese Pharmacopoeia limit table of similar pharmacopoeia for the residual solvents limited in cosmetics, the control over residual solvent of cosmetics will be more perfect to ensure that the products The quality and safety