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目的:了解新生儿先天性梅毒的临床特点,提高早期诊疗水平。方法:对2002年6月～2010年6月收治的32例新生儿先天性梅毒患儿的临床资料进行回顾性分析,总结其临床特征。结果:32例先天性梅毒患儿中有22例因母亲因素被建议入院,10例患儿因自身异常入院。无症状性先天性梅毒8例(25.0%),有症状性先天性梅毒24例(75.0%)。在腰椎穿刺成功的17例患儿中,有10例(58.8%)患有神经梅毒。30例经青霉素治疗,29例恢复正常。结论:早期先天性梅毒症状多不突出,易被漏诊,正规青霉素治疗,预后多良好。腰椎穿刺应该成为先天性梅毒的常规检查。
Objective: To understand the clinical features of neonatal congenital syphilis and improve the level of early diagnosis and treatment. Methods: The clinical data of 32 neonates with congenital syphilis admitted from June 2002 to June 2010 were retrospectively analyzed, and the clinical features were summarized. Results: Of 32 children with congenital syphilis, 22 were recommended for admission due to maternal factors and 10 were admitted to hospital due to their abnormality. Asymptomatic congenital syphilis in 8 cases (25.0%), symptomatic congenital syphilis in 24 cases (75.0%). Of the 17 children who succeeded in lumbar puncture, 10 (58.8%) had neurosyphilis. 30 cases of penicillin treatment, 29 cases returned to normal. Conclusion: Symptoms of early congenital syphilis are not prominent, easily missed diagnosis, regular penicillin treatment, prognosis and more good. Lumbar puncture should be routine examination of congenital syphilis.