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目的探讨药物联合饮食控制、运动疗法治疗社区老年2型糖尿病(2-DM)的临床疗效。方法选取厦门市湖里区殿前街道社区卫生服务中心2014年6月—2015年8月收治的老年2-DM患者96例,采用随机数字表法分为对照组与研究组,各48例。对照组予以药物治疗,研究组在对照组基础上予以饮食控制、运动疗法治疗,两组患者均持续治疗3个月。比较两组患者的临床疗效、治疗前后空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平、健康检查量表(SF-36)评分及不良反应发生情况。结果研究组患者临床疗效优于对照组(P<0.05)。治疗前两组患者FPG、2 h PG、HbA_(1c)水平比较,差异无统计学意义(P>0.05);治疗后研究组患者FPG、2 h PG及HbA_(1c)水平低于对照组(P<0.05)。治疗前两组患者SF-36评分比较,差异无统计学意义(P>0.05);治疗后研究组患者SF-36评分高于对照组(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论药物联合饮食控制、运动疗法治疗社区老年2-DM的临床疗效确切,可有效稳定患者的血糖水平,提升生活质量。
Objective To investigate the clinical efficacy of drug combination diet control and exercise therapy in the treatment of community-aged type 2 diabetes mellitus (DM). Methods A total of 96 elderly patients with 2-DM were enrolled in the community health service center of Dianqian Street, Huli District, Xiamen from June 2014 to August 2015, and divided into control group and study group by random number table. The control group was treated with drugs. The study group was given diet control and exercise therapy on the basis of the control group. Both groups were treated for 3 months. The clinical efficacy, fasting blood glucose (FPG), 2 h PG and HbA1c levels, SF-36 scores and adverse reactions in both groups were compared before and after treatment. Results The clinical efficacy of the study group was better than that of the control group (P <0.05). The levels of FPG, 2 h PG and HbA 1c in the two groups before treatment were not significantly different (P> 0.05). The levels of FPG, 2 h PG and HbA 1c in the study group were lower than those in the control group P <0.05). There was no significant difference in SF-36 score between the two groups before treatment (P> 0.05). SF-36 score of study group was higher than that of control group (P <0.05). Two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion The combination of drug and diet control and exercise therapy in the treatment of community elderly 2-DM has definite curative effect, which can effectively stabilize the blood glucose level and improve the quality of life.