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背景:已经有两例输注溶剂/去污剂处理的同批抗血友病因子Ⅷ浓制剂感染甲肝病毒的事实被监控系统报导。作者进行了一项调查研究,其目的是为了发现另外的病例,并确定其感染源。 研究设计与方法:对于接触了最近有血清学证据怀疑能传染甲型肝炎病毒(HAV)的批次的人群进行了一次流行病学调查。结果:最近发现的6例HAV感染者,其中4例已注射可疑因子Ⅷ浓制剂批次.2例输注了与可疑因子Ⅷ批次同一混合血浆提
BACKGROUND: The fact that two identical HeparinFVIII concentrates infused with solvent / detergent have been infected with Hepatitis A virus has been reported by surveillance systems. The authors conducted a research study aimed at identifying additional cases and identifying their source of infection. Study Design and Methodology: An epidemiological survey was conducted of people exposed to batches of individuals suspected of being infected with Hepatitis A virus (HAV) recently on serological evidence. Results: Of the 6 recently discovered HAV infected individuals, 4 had been challenged with a batch of suspect factor VIII concentrate and 2 had been infused with the same mixed plasma of suspicious factor Ⅷ batches