干细胞移植可改善心脏功能,其机制可能为移植的细胞分化为心肌细胞,促进宿主细胞分泌促进血管生成的细胞因子及改善宿主心脏局部结构,提高局部心肌弹力,参与宿主心脏收缩。回顾近年相关权威研究,基础临床研究均证实干细胞移植治疗扩张型心肌病合并心力衰竭是一项安全有效的干预措施。 Stem cell transplantation can improve cardiac function. The mechanism may be that the transplanted cells differentiate into cardiomyocytes, promote the secretion of cytokines that promote angiogenesis and improve the local structure of the host heart, enhance the local myocardial elasticity, and participate in the contraction of the host heart. Review of the relevant authoritative research in recent years, basic clinical studies have confirmed that stem cell transplantation for the treatment of dilated cardiomyopathy with heart failure is a safe and effective intervention.