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目的:探讨婴幼儿原发生皮肤骨瘤的临床病理特征。方法:大体及镜下观察,结合临床表现及X线检查并文献复习。结果:4例患儿,2男2女,年龄为5个月~4岁,临床表现为背部、颈部、腕部及腹股沟红褐色条索状及结节状皮疹,质硬。病理学特征:大体见切除皮肤局部稍高出皮面,质硬,边界清。镜检见真皮及皮下组织中见成片、成团分布的骨及骨样组织,由成熟编织骨组成,周围可见骨母细胞。结论:皮肤骨瘤指真皮或皮下组织内新骨形成,可分为原发性及继发性,该病为良性肿瘤,手术切除治疗效果好,未见恶变报道。
Objective: To investigate the clinicopathological features of primary osteoma in infants and young children. Methods: General and microscopic observation, combined with clinical manifestations and X-ray examination and literature review. Results: There were 4 children, 2 males and 2 females, aged from 5 months to 4 years old. The clinical manifestations were reddish-brown cord and nodular rash on the back, neck, wrists and groin. Pathological features: Generally see the excision of the skin slightly higher than the skin, hard, clear boundary. Microscopic examination of the dermis and subcutaneous tissue see into pieces, into the group distribution of bone and bone-like tissue, composed of mature braided bone around the visible bone cells. Conclusion: Dermal osteoma refers to the formation of new bone in the dermis or subcutaneous tissue. It can be divided into primary and secondary. The disease is a benign tumor. Surgical resection is effective and no malignant transformation has been reported.