经血过多是放置宫内节育器(IUD)妇女的一个常见主诉,有时甚至导致取出。研究表明IUD可增加人子宫内膜的前列腺素E含量,因而人们设想用前列腺素合成酶抑制剂来减少IUD引起的过多的月经失血,关于甲灭酸的临床试用已有报告,本研究报告了另一个前列腺素合成酶抑制剂甲氧苯丙酸减少放置IUD妇女经血量的临床试验结果。研究对象为34例放置IUD后连续两个周期以上经血过多(平均血量>80ml)的健康妇女,盆腔检查 Menorrhagia (IUD) is a frequent complaint of menorrhagia and sometimes leads to withdrawal. Studies have shown that IUD can increase endometrial prostaglandin E levels, so one envisions using prostaglandin synthase inhibitors to reduce excessive menstrual bleeding caused by IUD, clinical trials of mefenamic acid have been reported, the study report Another prostaglandin synthetase inhibitor, metoprofen, reduces clinical menstrual flow in women with IUD. Participants were 34 healthy women who had two or more consecutive menstrual cycles with IUD (mean blood volume> 80ml), pelvic examination