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目的探讨儿童暴发抑制型脑电图的病因及预后。方法2004—2006年武汉市儿童医院通过住院观察及脑电图、头颅CT和(或)MRI等辅助检查,对40例具有暴发抑制型脑电图患儿的临床资料进行分析。结果在40例儿童暴发抑制型脑电图中,大田原综合征(OS)17例(40%),婴儿痉挛15例(36%),病毒性脑炎4例,急性脑梗死2例,异物导致缺氧缺血性脑病2例。其中36例(86%)伴有精神发育迟滞。结论儿童暴发抑制型脑电图改变并无特异性,可由诸多严重的弥漫性脑部疾病引起,是预后不良的征兆;其预后情况与不同病因关系密切。
Objective To investigate the etiopathogenesis and prognosis of children with outbreak suppression EEG. Methods From 2004 to 2006, Wuhan Children ’s Hospital analyzed the clinical data of 40 children with outbreak inhibitory electroencephalogram (EEG) through inpatient observation, EEG, CT and / or MRI. Results Of the 40 children with outbreak suppression EEG, 17 (40%) had Osteoporosis syndrome (OS), 15 (36%) infantile spasms, 4 viral encephalitis, 2 acute cerebral infarction and foreign body Hypoxic ischemic encephalopathy in 2 cases. Of these, 36 (86%) had mental retardation. Conclusions Children with outbreak inhibitory electroencephalogram has no specific change, which can be caused by many serious diffuse brain diseases and is a sign of poor prognosis. The prognosis is closely related to different etiologies.