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目的调查本院及市中医院阴沟肠杆菌分布及耐药状况,为临床合理用药提供依据。方法采用美国Micro Scan auto SCAN4微生物分析仪及革兰阴性复合板进行菌株鉴定与药敏试验。结果2006年1月至2008年1月从痰液(60.3%)、切口分泌物(22.6%)、尿液(10.3%)等标本中分离出阴沟肠杆菌106株,耐药率呈逐上升趋势,对阿米卡星耐药率较低,亚胺培南敏感仍保持较高的敏感率,而对其他16种抗生素耐药率均>48.0%。结论医院应加强对阴沟肠杆菌耐药监测,以防医院感染的发生及暴发流行。
Objective To investigate the distribution and drug resistance status of Enterobacter cloacae in our hospital and the Chinese medicine hospital, and to provide basis for clinical rational drug use. Methods Micro Scan auto SCAN4 Microbial Analyzer and Gram-negative composite plates were used to identify strains and drug susceptibility test. Results From January 2006 to January 2008, 106 strains of Enterobacter cloacae were isolated from sputum (60.3%), incisional secretions (22.6%) and urine (10.3%). The drug resistance rates showed an upward trend , The resistance rates to amikacin were low, and the sensitivity of imipenem remained high, while the resistance rate to other 16 antibiotics was> 48.0%. Conclusion The hospital should strengthen the monitoring of Enterobacter cloacae drug resistance to prevent the occurrence of hospital infection and outbreak.