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目的:探讨术中直视下植入125I粒子与外科手术联合应用治疗肺癌的方法,并初步评价其治疗效果。方法:选择我院20例肺癌患者,在治疗计划系统指导下,常规手术切除肺瘤体后,术中直视下将125I粒子植入到肿瘤残留部分,手术无法切除的转移的淋巴结或细胞易播散部位,观察并初步评价其疗效。结果:本组20例患者术后观察2～10个月,均生存而无肿瘤复发,其中3例肿瘤残留部分明显缩小,1例患者治疗后6个月出现脑转移,1例患者治疗后1个月出现骨转移;所有患者术后恢复均良好,无明显不良反应及并发症。结论:术中直视下植入125I粒子并与手术相结合治疗肺癌初期疗效显著,弥补了化疗和常规外放疗的不足,为难以治疗的或部分晚期的肺癌患者提供了生存机会,提高了患者的生活质量。
Objective: To explore the method of combined operation of 125I seeds and surgical operation in the treatment of lung cancer under direct vision, and to evaluate its therapeutic effect. Methods: Twenty patients with lung cancer in our hospital were selected. Under the guidance of the treatment planning system, 125I seeds were implanted into the residual part of the tumor under routine surgery after removal of the lung tumor. The unresectable lymph nodes or cells Disseminated site, observe and preliminary evaluation of its efficacy. Results: Twenty patients in this group were observed for 2 to 10 months postoperatively, all survived without recurrence of tumor. Three of the tumor residuals were significantly reduced, one patient had brain metastases at 6 months after treatment, and one patient had 1 Month bone metastases; all patients recovered well, no significant adverse reactions and complications. CONCLUSIONS: 125I seeds are implanted under direct vision and combined with surgery in the treatment of lung cancer have a significant initial effect, which can make up for the lack of chemotherapy and conventional external radiotherapy and provide opportunities for survivors of refractory or partially advanced lung cancer and improve the patients’ The quality of life