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目的研究海南核果木(Drypetes hainanensis Merr.)枝叶中苯丙素类化学成分。方法通过多种色谱技术进行分离纯化,包括硅胶柱色谱、Sephadex LH-20柱色谱、MCI、高效液相色谱等方法,利用理化数据和波谱技术分析确定化合物的结构。结果与结论从海南核果木干燥枝叶的正丁醇提取物中分离得到8个已知苯丙素类化合物,分别鉴定为erythro-7-methoxyguaiacylglycerol(1)、threo-7-methoxyguaiacylglycerol(2)、erythro-7-methoxysyringylglycerol(3)、threo-7-methoxysyringylglycerol(4)、erythro-guaiacylglycerol(5)、threo-guaiacylglycerol(6)、erythro-syringylglycerol(7)、threo-syringylglycerol(8)。所有化合物均为首次从该植物中分离得到。
Objective To study the chemical constituents of phenylpropanoids in the branches and leaves of Drypetes hainanensis Merr. Methods The compounds were separated and purified by a variety of chromatographic techniques, including silica gel column chromatography, Sephadex LH-20 column chromatography, MCI and high performance liquid chromatography. The structures of the compounds were determined by physico-chemical data and spectral analysis. RESULTS AND CONCLUSION: Eight known phenylpropanoids were isolated from the n-butanol extracts of dried branches and leaves of S. dipsacus and identified as erythro-7-methoxyguaiacylglycerol (1), threo-7-methoxyguaiacylglycerol -7-methoxysyringylglycerol (3), threo-7-methoxysyringylglycerol (4), erythro-guaiacylglycerol (5), threo-guaiacylglycerol (6), erythro-syringylglycerol (7), threo-syringylglycerol (8). All compounds were isolated from this plant for the first time.