论文部分内容阅读
本文对23例胆囊癌,9例腺瘤,105例胆囊腺上皮增生的病例进行了组织病理学和核仁组成区相关嗜银蛋白(AgNOR)染色观察,发现长期的胆囊炎、胆石症引起胆囊粘膜上皮增生,以致发展为不典型增生,最后导致癌变的过程。AgNOR染色显示出上皮从单纯性增生,不典型增生到癌变银颗粒数目持续性增加,颗粒持续性增大,良恶性病变AgNOR数目差异有显著性(p<0.001。)
In this study, 23 cases of gallbladder carcinoma, 9 cases of adenoma, and 105 cases of gallbladder gland epithelial hyperplasia were examined for histopathology and AgNOR staining. It was found that chronic cholecystitis and cholelithiasis caused gallbladder Epithelial hyperplasia, resulting in the development of atypical hyperplasia, eventually leading to the process of cancer. AgNOR staining showed that the number of epithelial cells from simple hyperplasia, atypical hyperplasia to cancerous silver particles increased persistently, and the particles continued to increase. The number of AgNOR in benign and malignant lesions was significantly different (p<0.001).