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目的观察蒙脱石散剂联合阿莫西林治疗儿科消化性溃疡的临床疗效。方法选取某院儿科2012年5月—2014年10月收治的100例消化性溃疡患儿为研究对象,分为对照组与研究组,各50例。对照组给予阿莫西林治疗,研究组给予蒙脱石散剂联合阿莫西林治疗,2周为1个疗程,治疗4个疗程。比较两组的临床疗效、不良反应发生情况、症状评分变化情况及幽门螺杆菌根除率。结果对照组患儿幽门螺杆菌根除率、总有效率均低于研究组,不良反应发生率高于研究组,各症状评分高于研究组,差异有统计学意义(P<0.05)。结论蒙脱石散联合阿莫西林治疗儿科消化性溃疡的疗效确切、不良反应少、安全性高。
Objective To observe the clinical efficacy of montmorillonite powder combined with amoxicillin in the treatment of pediatric peptic ulcer. Methods A total of 100 children with peptic ulcer admitted to our hospital from May 2012 to October 2014 were selected as control group and study group, 50 cases each. The control group was treated with amoxicillin, and the study group was treated with montmorillonite powder and amoxicillin. The course was 2 weeks for 1 course of treatment and 4 courses of treatment. The clinical efficacy, incidence of adverse reactions, symptom scores and Helicobacter pylori eradication rates were compared between the two groups. Results The eradication rate and total effective rate of Helicobacter pylori in children in control group were lower than those in study group. The incidence of adverse reactions was higher in study group than in study group. The scores of each symptom were higher than those in study group (P <0.05). Conclusion Montmorillonite powder combined with amoxicillin treatment of pediatric peptic ulcer is effective, less adverse reactions, high safety.