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已知正常 CBA 小鼠感染疟原虫 P.berg-hei yoelii 15～18天后可自愈,此后便具有免疫力。为了进一步研究产生获得免疫的体液和细胞因素,作者用免疫小鼠血清和细胞被动转移方法进行了一系列实验。实验用雄性 CBA/LAC 小鼠(鼠龄8～15周),凡需去除 T 细胞的,则在生后7周切除胸腺,并经 X 线照射和同系骨髓细胞移植。感染均用约氏鼠疟原虫的17X 株经腹腔途径进行,其具体接种方法以及血中疟原虫数
It is known that normal CBA mice are self-healing after being infected with P. bergheii yoelii for 15 to 18 days and thereafter become immune. To further investigate the humoral and cellular factors that produce immunity, the authors conducted a series of experiments using immunized mouse serum and passive cell transfer methods. Experimental male CBA / LAC mice (8 to 15 weeks of age) where thymus is removed 7 weeks after birth, and irradiated with X-ray and homologous bone marrow cells are transplanted. Infections were about 17X strain of P. murine parasite via the abdominal route, the specific method of inoculation as well as the number of blood malaria parasites