论文部分内容阅读
目的:探讨动脉内留置导管持续灌注化疗联合胃左/胃右动脉栓塞术治疗中晚期胃底-贲门癌的应用价值及临床效果。方法:选取我院79例中晚期胃底-贲门癌,男48例,女31例。经股动脉穿刺,采用Seldinger技术经股动脉插管将导管置于腹腔动脉超选胃左动脉、胃右动脉,进行血管造影。动脉内留置导管微量泵灌注化疗药物表阿霉素(EADM)、丝裂霉素(MMC)、奥沙利铂(OXA)、5-氟尿嘧啶(5-FU),再使用超液化碘(UFL)与表阿霉素(EADM)混合成碘油乳剂+明胶海绵颗粒行胃左动脉栓塞术。结果:近期有效率显著提高,复查病例中原发病灶、区域淋巴结转移及转移灶有不同程度减小,临床症状减轻,全组未发生严重副作用及并发症。完全缓解(CR)16例、部分缓解(PR)47例、稳定(SD)22例、病灶进展(PD)4例。结论:动脉内留置导管持续灌注化疗联合栓塞术治疗中晚期胃底-贲门癌能改善患者的生存质量,提高生存率,是治疗中晚期胃底-贲门癌的有效方法。
Objective: To investigate the clinical value of continuous intra-arterial catheter infusion chemotherapy combined with left / right gastric artery embolization in the treatment of advanced gastric cardia-cardia cancer. Methods: Selected 79 cases of advanced gastric fundus - cardia cancer, 48 males and 31 females. The femoral artery puncture, the use of Seldinger technology via femoral artery catheter placed in the celiac artery surgeries of the left gastric artery, right gastric artery, angiography. Intravenous indwelling catheter infusion pump chemotherapy epirubicin (EADM), mitomycin (MMC), oxaliplatin (OXA), 5-fluorouracil (5-FU), then the use of ultra-liquefied iodine (UFL) And epirubicin (EADM) mixed into lipiodol emulsion + gelatin sponge particles left gastric artery embolization. Results: The recent efficiency was significantly improved. The primary lesion, regional lymph node metastasis and metastasis in the reexamined cases decreased to some extent, and the clinical symptoms were relieved. There were no serious side effects and complications in the whole group. There were 16 cases of complete remission (CR), 47 cases of partial remission (PR), 22 cases of stable (SD) and 4 cases of lesion progression (PD). Conclusion: Intra-arterial infusion catheter infusion chemotherapy combined with embolization in the treatment of advanced gastric cardia and gastric cardia cancer can improve the quality of life of patients and improve survival rate. It is an effective method for the treatment of advanced gastric cardia and cardia cancer.