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近10多年来诱变物和致癌物的生物学学短期试验发展异常迅速,其中以鼠伤寒沙门氏菌/微粒体酶系统(简称Ames试验)更为突出。自1973年Ames及其同事发表实验方法以来,目前全世界有2,000多个实验室采用此法进行研究工作,已筛选过的化学物达5,000余种。国内以复旦大学遗传所、天津劳动卫生研究所等单位较早开展此项工作。《工业毒理学实验方法》一书对Ames试
Nearly 10 years of mutagen and carcinogen biological short-term rapid development of the experiment, of which the Salmonella typhimurium / microsomal enzyme system (referred to as Ames test) is more prominent. Since Ames and his colleagues published the experimental method in 1973, more than 2,000 laboratories around the world have used this method to conduct research. There are over 5,000 chemicals that have been screened. Domestic Fudan University Institute of Genetics, Tianjin Institute of Labor and Health and other units to carry out this work earlier. Ames Tests for Industrial Toxicology