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目的：观察醒脑静注射液治疗血管性痴呆（ Ｖ Ｄ）的疗效，及对高密度脂蛋白（ Ｈ Ｄ Ｌ）、低密度脂蛋白（ Ｌ Ｄ Ｌ）的影响。方法：根据痴呆简易筛查量表，于治疗前后评分，治疗组采用醒脑静１０～２０ ｍ ｌ静点，对照组采用胞二磷胆碱 ０５～１０ ｇ 静点，每日 １ 次，并观察治疗前后 Ｈ Ｄ Ｌ 和 Ｌ Ｄ Ｌ 的变化情况。结果：治疗组病人治疗后智能评分与对照组比较差异非常显著（ Ｐ＜ ００１）， Ｈ Ｄ Ｌ 治疗后较对照组升高非常显著（ Ｐ＜ ００１）， Ｌ Ｄ Ｌ 下降非常显著（ Ｐ＜ ００１）。结论：醒脑静注射液治疗 Ｖ Ｄ 能明显改善临床症状，并能使 Ｈ Ｄ Ｌ 升高， Ｌ Ｄ Ｌ 下降，使 Ｖ Ｄ 患者脂代谢紊乱得到改善。
Objective: To observe the efficacy of Xingnaojing injection in the treatment of vascular dementia (VD) and the effects of high-density lipoprotein (HDL) and low-density lipoprotein (LDL). Methods: According to the simple screening scale for dementia, scores before and after treatment were used. The treatment group was treated with Xingnaojing 10 ~ 20 m l static point, and the control group was treated with Citicoline 05 ~ 10 g static point, daily 1 time, and observed changes in HLD and LDL before and after treatment. Results: There was a significant difference between the treatment group and the control group after the treatment group (P < 0 01), and it was significantly higher after the H D L treatment than in the control group (P < 0 01). The drop of L D L was very significant. (P<001). Conclusion: Xingnaojing injection can significantly improve the clinical symptoms of VD, and can increase the HLD and LDL, and improve the lipid metabolism disorder in VD patients.