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目的观察自拟复感汤对反复呼吸道感染土虚木乘型儿童Th17细胞的影响及对临床症状的改善作用。方法将100例反复呼吸道感染土虚木乘型患儿随机分为2组,对照组51例口服匹多莫德,治疗组49例口服自拟复感汤,治疗1月后比较2组患儿的总有效率、Th17细胞的变化以及1年内发病情况。结果治疗组总有效率为91.8%,对照组为74.5%,2组比较差异有统计意义(P<0.05);治疗后2组Th17细胞百分比均较治疗前降低,但对照组无统计意义,治疗组有高度统计意义(P<0.01);治疗后1年内2组发病次数及发病时间均减少,且治疗组减少更为明显(P<0.05或P<0.01)。结论自拟复感汤治疗儿童反复呼吸道感染土虚木乘型疗效明显,且对外周血Th17细胞有明显的降低作用。
Objective To observe the effect of self-made Fu-Tang on Th17 cells in Thompson seed-bearing children with recurrent respiratory tract infection and to improve the clinical symptoms. Methods 100 cases of children with recurrent respiratory tract infection of Astragalus mongholicus were randomly divided into two groups, 51 cases in the control group were treated with Pidotimod, and 49 cases in the treatment group were given Fufang Soup. After one month, the two groups were compared The total effective rate, Th17 cell changes and the incidence of disease within 1 year. Results The total effective rate was 91.8% in the treatment group and 74.5% in the control group, the difference between the two groups was statistically significant (P <0.05). The percentages of Th17 cells in the two groups after treatment were lower than those before treatment, but the control group had no statistical significance (P <0.01). The number of onset and the onset time of the two groups decreased within one year after treatment, and the treatment group decreased more obviously (P <0.05 or P <0.01). Conclusion Self-made Fu-Tang Decoction treatment of children with recurrent respiratory tract infection Xuxue significant effect, and on the peripheral blood Th17 cells significantly reduced.