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目的:分析感染性休克时血乳酸浓度、血镁浓度变化及相关性。方法:将26例患者分为感染性休克组(Ⅰ组,13例)和非休克组(Ⅱ组,13例),分析两组患者血乳酸浓度和血清总镁及游离镁浓度的变化以及相关性。同时比较两组患者APACHEⅡ评分、平均动脉压(MAP)、动脉血氧分压(PaO2)和死亡率。结果:感染性休克组的乳酸浓度、APACHEⅡ评分和死亡率显著高于非休克组;血清总镁及游离镁浓度、平均动脉压和动脉血氧分压显著低于非休克组;休克组血乳酸浓度与APACHEⅡ评分、血清总镁和游离镁浓度的相关系数分别为0.616、-0.935和-0.938。结论:血乳酸浓度升高和镁缺乏是感染性休克的重要特点,且可反映休克程度,评估预后。
Objective: To analyze the changes of blood lactic acid concentration and blood magnesium concentration in septic shock and its correlation. Methods: Twenty-six patients were divided into septic shock group (group Ⅰ, n = 13) and non-shock group (group Ⅱ, n = 13). The changes of blood lactic acid concentration and serum total magnesium and free magnesium concentration Sex. APACHEⅡscore, mean arterial pressure (MAP), PaO2 and mortality were compared between the two groups. Results: Lactic acid concentration, APACHEⅡscore and mortality in septic shock group were significantly higher than those in non-shock group. Serum total magnesium and free magnesium concentration, mean arterial pressure and arterial oxygen pressure were significantly lower than those in non-shock group. The correlation coefficient between APACHEⅡscore and serum total magnesium and free magnesium concentration were 0.616, -0.935 and -0.938, respectively. Conclusion: Elevated blood lactate and magnesium deficiency are important features of septic shock, and can reflect the degree of shock and evaluate the prognosis.