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微血管密度 (Microvessel.Density简称 MVD)测定 ,与子宫颈癌预后有一定关系 ,据文献报导 MVD≤ 2 0 /每视野有94%左右患者可以存活 5年以上 ,而 MVD>2 0 /每视野仅有 2 9%左右患者存活 〔1〕。本文对 2 0例宫颈肿瘤组织标本采用免疫组化方法进行微血管密度测定分析 ,其结果 >2 0 /每视野有 13例 (13/2 0 )占 6 5 % ,≤ 2 0 /每视野有 7例 (7/2 0 )占 35 % ,同时比较了微血管密度与肿瘤临床分期有一定关系。宫颈 期癌 6例≤ 2 0 /每视野有 5例 (5 /6 )占 83% ,宫颈 - 期鳞癌、腺癌 14例。 >2 0 /每视野有 12例 (12 /14)占 83%。通过测定 MVD有助于帮助指导临床治疗及对肿瘤预后分析。
Microvessel density (Microvessel.Density referred to as MVD) determination, and prognosis of cervical cancer have a certain relationship, according to the literature reported that MVD≤ 20 / per field of vision about 94% of patients can survive more than 5 years, and MVD> 20 / per field of view only About 29% of patients survive [1]. In this paper, 20 cases of cervical cancer tissue samples by immunohistochemical analysis of microvessel density, the results> 20 / per field of vision in 13 cases (13/2 0) accounted for 65%, ≤ 20 / per field of vision 7 Cases (7/2 0) accounted for 35%, while comparing the microvessel density and tumor clinical stage has a certain relationship. Cervical cancer in 6 cases ≤ 20 / per field of vision in 5 cases (5/6) accounted for 83%, cervical - stage squamous cell carcinoma, adenocarcinoma in 14 cases. > 20/12 per field of view (12/14) accounted for 83%. By measuring MVD helps to guide the clinical treatment and prognosis of the tumor.