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目的探讨奥曲肽联合兰索拉唑治疗上消化道出血患者的临床效果。方法选取急诊内科收治的86例上消化道出血患者为研究对象,按随机数字表法将其分为对照组和观察组,每组43例。对照组患者单纯给予兰索拉唑治疗,观察组患者给予奥曲肽联合兰索拉唑治疗,比较两组患者的临床疗效。结果治疗后对照组患者总有效率为76.7%,观察组患者总有效率高达95.3%,差异有统计学意义(P<0.05)。观察组患者的止血时间和住院时间均明显短于对照组,差异均有统计学意义(均P<0.05)。但两组患者不良反应比较,差异无统计学意义(P>0.05)。结论奥曲肽联合兰索拉唑治疗上消化道出血疗效明显,可快速实现止血,缩短住院时间,且不良反应少。
Objective To investigate the clinical effect of octreotide combined with lansoprazole on patients with upper gastrointestinal hemorrhage. Methods A total of 86 cases of upper gastrointestinal bleeding admitted to the department of emergency medicine were selected as the research object. According to the random number table, they were divided into control group and observation group, with 43 cases in each group. The patients in the control group were treated with lansoprazole alone. The patients in the observation group were treated with octreotide combined with lansoprazole, and the clinical efficacy was compared between the two groups. Results After treatment, the total effective rate of the control group was 76.7%, and the total effective rate of the observation group was 95.3%, the difference was statistically significant (P <0.05). The bleeding time and length of stay in observation group were significantly shorter than those in control group (all P <0.05). However, there was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Octreotide combined with lansoprazole treatment of upper gastrointestinal bleeding has obvious curative effect, which can quickly stop bleeding and shorten hospital stay with less adverse reactions.