用离体灌注的大鼠心模拟局部缺血及再灌注探讨再灌注对肌纤维的损伤和促进收缩带形成的作用.表明收缩带起源于交界性损伤阶段的肌纤维.将收缩带分为节段、条带、枝条和碎片四型,延长缺血及再灌注时间,则前两型数量减少而第三型数量增加,肌纤维挛缩时肌节极度缩短,导致横管牵拉胞膜,易造成膜破裂.加速肌纤维坏死. In vitro perfusion of rat hearts simulated ischemia and reperfusion injury reperfusion on the muscle fibers and promote the formation of the role of the contraction zone, indicating that the contraction zone originated in the junction of the injury phase of the muscle fibers.The contraction zone is divided into segments, Strips, branches and fragments of four, to extend the ischemia and reperfusion time, the first two types of reduced number and the third increase in the number of muscle fiber contractures when the shortest muscle suture, leading to cross-tube stretch cell membrane, easy to cause membrane rupture Accelerate muscle fiber necrosis.