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单核细胞趋化蛋白-1(MCP-1)是CC类趋化因子家族中的主要成员之一,对单核细胞、巨噬细胞、淋巴细胞具有很强的趋化活性,在免疫炎症反应、动脉粥样硬化、HIV感染等一系列疾病过程中发挥重要作用。近年来其在胰腺炎的发病和疾病发展中所起的作用越来越受到重视。本文就MCP-1与胰腺炎关系的研究进展作一综述。
Monocyte Chemotactic Protein-1 (MCP-1) is one of the major members of CC chemokines and has a strong chemotactic activity on monocytes, macrophages and lymphocytes. In the immune-inflammatory response , Atherosclerosis, HIV infection and a series of diseases play an important role in the process. In recent years, its role in the pathogenesis of pancreatitis and disease play an increasingly important role. This article reviews the progress of research on the relationship between MCP-1 and pancreatitis.