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目的:探究老年心肌梗死患者经皮冠状动脉介入治疗(PCI)术后心率变异性的变化及实施PCI治疗后给予丹参滴丸的临床疗效。方法:收集2015年3月到2016年3月来我院就诊的老年急性心肌梗死患者56例,根据随机数字表法分为试验组及对照组,各28例,对所有患者实施PCI术,术后对照组使用基础药物治疗,试验组使用基础药物治疗联合复方丹参滴丸。比较PCI治疗前后心率变异性的变化及两组患者的心功能。结果:PCI术后,患者测定指标SDNN、SDNN Index及SDANN相对于术前均有升高(P<0.05);频域分析指标HF及LF相对于术前均升高,LF/HF比值降低(P<0.05)。治疗结束后,两组患者LVEF、SV及CI均明显升高,LVEDD明显降低(P<0.05),与对照组相比,试验组患者LVEF、SV及CI较高,LVEDD较低(P<0.05)。结论:PCI术能够改善老年心肌梗死患者心率变异性,而复方丹参滴丸对于PCI术后老年心肌梗死患者心功能指标均有明显改善,临床疗效较好。
Objective: To investigate the changes of heart rate variability after percutaneous coronary intervention (PCI) in elderly patients with myocardial infarction and the clinical efficacy of Danshen dripping pills after PCI. Methods: Fifty-six elderly patients with acute myocardial infarction who came to our hospital from March 2015 to March 2016 were divided into experimental group and control group according to the random number table method, 28 cases in each group. PCI was performed on all patients After the control group using the basic drug treatment, the experimental group using the basic drug treatment combined with compound Danshen dripping pills. The changes of heart rate variability before and after PCI and the cardiac function of two groups were compared. Results: The indexes of SDNN, SDNN Index and SDANN in patients after PCI were significantly higher than those before operation (P <0.05). The frequency of HF and LF were higher than those before operation and the LF / HF ratio was decreased P <0.05). After treatment, LVEF, SV and CI were significantly increased and LVEDD were significantly decreased in both groups (P <0.05). Compared with the control group, LVEF, SV and CI were higher in the trial group and LVEDD was lower (P <0.05 ). Conclusion: PCI can improve the heart rate variability in elderly patients with myocardial infarction. However, the compound Danshen dripping pills have significantly improved cardiac function in elderly patients with myocardial infarction after PCI, and the clinical curative effect is better.