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目的探讨乳腺癌化疗患者PICC的应用和护理措施以及护理体会。方法回顾性分析我科收治的乳腺癌患者48例在化疗中应用PICC的分析讨论，实施PICC操作时注意严格执行无菌操作技术，在使用PICC期间实施护理干预，针对PICC发生的相关并发症采取相应的护理对策。结果此组患者PICC一次性穿刺成功率为83.3%，使用过程中发生并发率为6.2%。其中静脉炎1例，导管堵塞1例，导管脱出1例，感染0例。结论乳腺癌患者化疗中进行PICC置管可以提高化疗的治疗效果，减少外周静脉穿刺带来的痛苦，严格掌握PICC技术的操作与护理措施能够预防和降低各种并发症的发生，对于并发症采取针对性的护理能够减少临床危险发生。“,” Objective: To explore the experience of patients with PICC chemotherapy for breast cancer and nursing measures and nursing. Methods: retrospective analysis of our hospital 48 cases of breast cancer patients during chemotherapy was analyzed using the PICC discussion, implementation of PICC operation attention to strict implementation of aseptic technique, the implementation of nursing intervention during the using of PICC, adopt the corresponding nursing countermeasures for complications related to PICC occurred. Results: the success rate of this group of patients with PICC disposable puncture was 83.3%, occurred during concurrent rate was 6.2%. Including 1 cases of phlebitis, catheter obstruction in 1 cases, 1 cases of catheter prolapse, infection in 0 cases. Conclusion: PICC catheter can improve the treatment effect of chemotherapy in patients with breast cancer, reduce the pain of peripheral vein puncture, operation and nursing measures to strictly master the PICC technology can prevent and reduce various complications, the complications of the pertinent nursing can reduce clinical risk.