论文部分内容阅读
目的观察血必净对心肺复苏(CPR)后患者血清炎症介质的影响。方法经标准心肺复苏自主循环恢复(ROSC)后存活期≥3d的患者30例,随机分为血必净治疗组(A组)15例和对照组(B组)15例。血必净治疗组加用血必净注射液100ml静脉滴注,2次/d,连续3d,余治疗措施两组相同。观察比较两组复苏后即刻、第36、72小时血清TNF-α、IL-6和hs-CRP水平。结果治疗组血清TNF-α、IL-6和hs-CRP水平显著低于对照组。结论中药血必净有较好的控制炎症介质的作用,对心肺复苏患者的预后有益。
Objective To observe the effect of Xuebijing on serum inflammatory mediators in patients after cardiopulmonary resuscitation (CPR). Methods Thirty patients with survival ≥ 3 days after spontaneous circulation recovery (ROSC) of standard cardiopulmonary resuscitation were randomly divided into Xuebijing group (A group) and control group (15 cases). Xuebijing treatment group plus Xuebijing injection 100ml intravenous infusion, 2 times / d, continuous 3d, more than the same treatment measures in both groups. The levels of serum TNF-α, IL-6 and hs-CRP were observed at the 36th and 72th hour immediately after resuscitation. Results Serum levels of TNF-α, IL-6 and hs-CRP in the treatment group were significantly lower than those in the control group. Conclusion Traditional Chinese medicine Xuebijing has a better control of the inflammatory mediators, which is beneficial to the prognosis of CPR patients.