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目的观察黄葵胶囊联合洛汀新治疗慢性肾炎的疗效。方法将60例慢性肾炎患者随机分为黄葵胶囊联合洛汀新组(治疗组)和单用洛汀新组(对照组),分别检测两组治疗前后24h尿蛋白定量、血清白蛋白、血肌酐,并进行组间比较。结果治疗组临床疗效总有效率显著高于对照组(P<0.05);治疗组与对照组均能显著降低24h尿蛋白定量(P<0.05),两组比较有显著性差异(P<0.05);治疗组与对照组均能显著提高血清白蛋白(P<0.05),但两组比较无显著性差异(P>0.05);治疗组中治疗前血肌酐异常者用药后血肌酐显著下降(P<0.05)。结论黄葵胶囊具有清热利湿,消炎解毒,活血络和的功能,黄葵胶囊联合洛汀新治疗慢性肾炎比单用洛汀新能更显著地降低尿蛋白排泄量,改善肾功能,未见明显不良反应。
Objective To observe the efficacy of Huang Kui capsule combined with Lotensin in the treatment of chronic nephritis. Methods Sixty chronic glomerulonephritis patients were randomly divided into two groups: 24 hours pregnant group, 24 hours pregnant female group, 24 hours pregnant female group, 24 hours pregnant female group, Creatinine, and compared between groups. Results The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). The 24-hour urine protein of the treatment group and the control group were significantly lower than those of the control group (P <0.05) (P <0.05), but there was no significant difference between the two groups (P> 0.05). Serum creatinine in treatment group and control group were significantly decreased after treatment (P <0.05). Conclusion Huang Kui capsule has the functions of clearing away heat and dampness, detoxifying and detoxicating and promoting blood circulation, and Huan Kui capsule combined with Lotensin in treating chronic glomerulonephritis is more effective in reducing urinary protein excretion and improving renal function, Obvious adverse reaction.