手口足病是一种发疹性的季节性传染病,以夏秋季节患病最多,主要是由柯萨奇病毒引起~([1]),临床表现为手、足皮肤或口腔黏膜上出现类似水痘样的小疱疹,严重者可出现心肌炎、脑膜炎等并发症~([2-5])。手足口病以婴幼儿及学龄期儿 Hand-foot-mouth disease is a seasonal, contagious disease of the rash, predominantly attributable to the Coxsackie virus in the summer and fall (~ 1), with clinical manifestations similar to those seen on the hands, feet, or oral mucosa Smallpox-like smallpox, severe cases may occur myocarditis, meningitis and other complications ~ ([2-5]). Hand, foot and mouth disease to infants and school-age children