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为评价补硒对呼吸道合胞病毒(RSV)所致急性下呼吸道感染的疗效,采用双盲随机对照法,对75例1岁以下RSV感染的肺炎或毛细支气管炎住院患儿进行干预研究。结果表明,补硒组在症状、体征缓解天数方面短于常规治疗组,细胞免疫指标恢复正常者较常规治疗组多。补硒使血浆和白细胞中硒和谷胱甘肽过氧化物酶水平显著增高。本研究结果提示补硒可促进该病的恢复
To evaluate the efficacy of selenium supplementation in the treatment of acute lower respiratory tract infections caused by respiratory syncytial virus (RSV), 75 hospitalized children with pneumonia or bronchiolitis with RSV infection under the age of 1 were studied in a double-blind randomized controlled trial. The results showed that the selenium group was shorter than the conventional treatment group in the number of days of symptom and symptom relief, and the cellular immune indexes returned to normal more than the conventional treatment group. Selenium makes plasma and leukocyte selenium and glutathione peroxidase levels were significantly higher. The results suggest that selenium supplementation can promote the recovery of the disease